Butterfield, D. ., Barone, E. ., Di Domenico, F. ., Cenini, G. ., Sultana, R. ., Murphy, M. ., … Head, E. . (2012). Atorvastatin treatment in a dog preclinical model of Alzheimer’s disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain. The International Journal of Neuropsychopharmacology, 15(7), 981-7. https://doi.org/10.1017/S1461145711001118

Martin, S. ., Cenini, G. ., Barone, E. ., Dowling, A. ., Mancuso, C. ., Butterfield, D. ., … Head, E. . (2011). Coenzyme Q10 and cognition in atorvastatin treated dogs. Neuroscience Letters, 501(2), 92-5. https://doi.org/10.1016/j.neulet.2011.06.054 (Original work published 2011)

Barone, E. ., Di Domenico, F. ., Cenini, G. ., Sultana, R. ., Coccia, R. ., Preziosi, P. ., … Butterfield, D. . Oxidative and nitrosative modifications of biliverdin reductase-A in the brain of subjects with Alzheimer’s disease and amnestic mild cognitive impairment. Journal of Alzheimer’s Disease : JAD, 25(4), 623-33. https://doi.org/10.3233/JAD-2011-110092 (Original work published 2011)

Barone, E. ., Di Domenico, F. ., Cenini, G. ., Sultana, R. ., Cini, C. ., Preziosi, P. ., … Butterfield, D. . (2011). Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment. Biochimica Et Biophysica Acta, 1812(4), 480-7. https://doi.org/10.1016/j.bbadis.2011.01.005

Barone, E. ., Cenini, G. ., Di Domenico, F. ., Martin, S. ., Sultana, R. ., Mancuso, C. ., … Butterfield, D. . (2011). Long-term high-dose atorvastatin decreases brain oxidative and nitrosative stress in a preclinical model of Alzheimer disease: a novel mechanism of action. Pharmacological Research, 63(3), 172-80. https://doi.org/10.1016/j.phrs.2010.12.007

Barone, E. ., Cenini, G. ., Di Domenico, F. ., Noel, T. ., Wang, C. ., Perluigi, M. ., … Butterfield, D. . (2015). Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53. Journal of Neuroscience Research, 93(11), 1728-39. https://doi.org/10.1002/jnr.23627

Cenini, G. ., Fiorini, A. ., Sultana, R. ., Perluigi, M. ., Cai, J. ., Klein, J. ., … Butterfield, D. . (2014). An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach. Free Radical Biology & Medicine, 76, 89-95. https://doi.org/10.1016/j.freeradbiomed.2014.08.006

Fiorini, A. ., Sultana, R. ., Förster, S. ., Perluigi, M. ., Cenini, G. ., Cini, C. ., … Butterfield, D. . (2013). Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: a proteomics study. Free Radical Biology & Medicine, 65, 1-14. https://doi.org/10.1016/j.freeradbiomed.2013.06.017

Barone, E. ., Cenini, G. ., Sultana, R. ., Di Domenico, F. ., Fiorini, A. ., Perluigi, M. ., … Butterfield, D. . (2012). Lack of p53 decreases basal oxidative stress levels in the brain through upregulation of thioredoxin-1, biliverdin reductase-A, manganese superoxide dismutase, and nuclear factor kappa-B. Antioxidants & Redox Signaling, 16(12), 1407-20. https://doi.org/10.1089/ars.2011.4124 (Original work published 2012)

Cenini, G. ., Dowling, A. ., Beckett, T. ., Barone, E. ., Mancuso, C. ., Murphy, M. ., … Head, E. . (2012). Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome. Biochimica Et Biophysica Acta, 1822(2), 130-8. https://doi.org/10.1016/j.bbadis.2011.10.001