Pretreatment Donors after Circulatory Death with Simvastatin Alleviates Liver Ischemia Reperfusion Injury through a KLF2-Dependent Mechanism in Rat.
| Author | |
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| Abstract | :
Severe hepatic ischemia reperfusion injury (IRI) can result in poor short- and long-term graft outcome after transplantation. The way to improve the viability of livers from donors after circulatory death (DCD) is currently limited. The aim of the present study was to explore the protective effect of simvastatin on DCD livers and investigate the underlying mechanism. |
| Year of Publication | :
0
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| Journal | :
Oxidative medicine and cellular longevity
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| Volume | :
2017
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| Number of Pages | :
3861914
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| Date Published | :
2017
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| ISSN Number | :
1942-0900
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| DOI | :
10.1155/2017/3861914
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| Short Title | :
Oxid Med Cell Longev
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