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Age-dependent susceptibility to reovirus encephalitis in mice is influenced by maturation of the type-I interferon response.

Author
Abstract
:

Infants and young children are particularly susceptible to viral encephalitis, but the mechanisms are unknown. We determined the age-dependent contribution of innate and adaptive immune functions to reovirus-induced encephalitis in mice.

Year of Publication
:
2018
Journal
:
Pediatric research
Date Published
:
2018
ISSN Number
:
0031-3998
URL
:
http://dx.doi.org/10.1038/pr.2018.13
DOI
:
10.1038/pr.2018.13
Short Title
:
Pediatr Res
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