Lack of tolerance to the disinhibiting effects of alcohol in heavy drinkers.
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Abstract | :
Alcohol tolerance is observed as a diminished response to a given dose as a function of repeated administrations of the drug. Research has consistently shown that heavier drinkers display reduced reactions to alcohol (i.e., tolerance) compared with lighter drinkers. However, the majority of this work has focused primarily on measures of motor performance, whereas the development of tolerance to alcohol's impairing effects on cognitive processes, such as inhibitory mechanisms of behavioral control, remains relatively unexplored. |
Year of Publication | :
2012
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Journal | :
Psychopharmacology
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Volume | :
224
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Issue | :
4
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Number of Pages | :
511-8
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ISSN Number | :
0033-3158
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URL | :
https://doi.org/10.1007/s00213-012-2786-x
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DOI | :
10.1007/s00213-012-2786-x
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Short Title | :
Psychopharmacology (Berl)
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