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A case of mixed connective tissue disease positive for proteinase 3 antineutrophil cytoplasmic antibody in a patient with slowly progressive type 1 diabetes mellitus and chronic thyroiditis .

Author
Abstract
:

  A female in her sixties with slowly progressive type 1 diabetes mellitus (SPT1DM) and chronic thyroiditis was referred to our rheumatology department with swelling in her fingers. A prominent atherosclerotic lesion was revealed upon brain magnetic resonance imaging, and she was found to have mixed connective tissue disease (MCTD) positive for proteinase 3 (PR3)-antineutrophil cytoplasmic antibody (ANCA). This rare case of MCTD accompanying SPT1DM and PR3-ANCA suggested that a synergy between MCTD and PR3-ANCA triggers atherosclerosis.

Year of Publication
:
0
Journal
:
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology
Volume
:
40
Issue
:
6
Number of Pages
:
467-470
Date Published
:
2017
ISSN Number
:
0911-4300
URL
:
https://dx.doi.org/10.2177/jsci.40.467
DOI
:
10.2177/jsci.40.467
Short Title
:
Nihon Rinsho Meneki Gakkai Kaishi
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