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Farnesoid X receptor antagonist exacerbates dyslipidemia in mice.

Author
Abstract
:

The effects of farnesoid X receptor (FXR) antagonists on plasma lipid profile in mice have not been investigated thus far. The aim of this study was to investigate the antidyslipidemic effects of an FXR antagonist in dyslipidemic mice, and to clarify the mechanisms underlying the lipid modulatory effect.

Year of Publication
:
2017
Journal
:
Pharmacological reports : PR
Volume
:
70
Issue
:
1
Number of Pages
:
172-177
Date Published
:
2017
ISSN Number
:
1734-1140
URL
:
http://linkinghub.elsevier.com/retrieve/pii/S1734-1140(17)30091-9
DOI
:
10.1016/j.pharep.2017.07.010
Short Title
:
Pharmacol Rep
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