Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology.
| Author | |
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| Abstract | :
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia in the elderly population. In this study, we used the APP/PS1 transgenic mouse model to explore the feasibility of using diffusion kurtosis imaging (DKI) as a tool for the early detection of microstructural changes in the brain due to amyloid-β (Aβ) plaque deposition. |
| Year of Publication | :
2018
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| Journal | :
Alzheimer's research & therapy
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| Volume | :
10
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| Issue | :
1
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| Number of Pages | :
1
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| Date Published | :
2018
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| DOI | :
10.1186/s13195-017-0329-8
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| Short Title | :
Alzheimers Res Ther
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