A new enzyme-linked immunosorbent assay for neurofilament light in cerebrospinal fluid: analytical validation and clinical evaluation.
| Author | |
|---|---|
| Abstract | :
Cerebrospinal fluid (CSF) neurofilament light (NfL) is a reliable marker of neuro-axonal damage in different neurological disorders that is related to disease severity. To date, all recent studies performed in human CSF have used the same enzyme-linked immunosorbent assay (ELISA). To confirm the large body of evidence for NfL, we developed a new ELISA method and here we present the performance characteristics of this new ELISA for CSF NfL in different neurological disorders. |
| Year of Publication | :
2018
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| Journal | :
Alzheimer's research & therapy
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| Volume | :
10
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| Issue | :
1
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| Number of Pages | :
8
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| Date Published | :
2018
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| DOI | :
10.1186/s13195-018-0339-1
|
| Short Title | :
Alzheimers Res Ther
|
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