BANK1 alters B cell responses and influences the interactions between B cells and induced T regulatory cells in mice with collagen-induced arthritis.
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Abstract | :
Functional variants of the B cell gene, B cell scaffold protein with ankyrin repeats 1 (BANK1) contribute to rheumatoid arthritis (RA) susceptibility, but their influences on B cell responses are unclear. Moreover, the function of induced T regulatory cells (iTregs) in the inflammatory milieu in a collagen-induced arthritis (CIA) model is unknown. This study was performed to investigate the roles of BANK1 in CIA and the interaction between B cells and iTregs. |
Year of Publication | :
2018
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Journal | :
Arthritis research & therapy
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Volume | :
20
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Issue | :
1
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Number of Pages | :
9
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Date Published | :
2018
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ISSN Number | :
1478-6354
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DOI | :
10.1186/s13075-017-1503-x
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Short Title | :
Arthritis Res Ther
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