Preterm growth restriction and bronchopulmonary dysplasia: the vascular hypothesis and related physiology.
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Abstract | :
Approximately 5-10% pregnancies are affected by fetal growth restriction. Preterm infants affected by fetal growth restriction have a higher incidence of bronchopulmonary dysplasia. The present study is the first to measure pulmonary artery thickness and stiffness. The findings show that impaired vasculogenesis may be a contributory factor in the higher incidence of bronchopulmonary dysplasia in preterm growth restricted infants. The study addresses the mechanistic link between fetal programming and vascular architecture and mechanics. |
Year of Publication | :
2018
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Journal | :
The Journal of physiology
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Date Published | :
2018
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ISSN Number | :
0022-3751
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URL | :
https://doi.org/10.1113/JP276040
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DOI | :
10.1113/JP276040
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Short Title | :
J Physiol
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