Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects.
| Author | |
|---|---|
| Abstract | :
The physiological challenges posed by hypobaric hypoxia warrant exploration of pharmacological entities to improve acclimatization to hypoxia. The present study investigates the preclinical efficacy of sphingosine-1-phosphate (S1P) to improve acclimatization to simulated hypobaric hypoxia. |
| Year of Publication | :
0
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| Journal | :
PloS one
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| Volume | :
9
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| Issue | :
6
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| Number of Pages | :
e98025
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| Date Published | :
2014
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| URL | :
http://dx.plos.org/10.1371/journal.pone.0098025
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| DOI | :
10.1371/journal.pone.0098025
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| Short Title | :
PLoS One
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| Download citation |