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Thermodynamic stability of Hoogsteen and Watson-Crick base pairs in the presence of histone H3-mimicking peptide.

Author
Abstract
:

We found that Hoogsteen base pairs were stabilized by molecular crowding and a histone H3-mimicking peptide, which was not observed for Watson-Crick base pairs. Our findings demonstrate that the type of DNA base pair is critical for the interaction between DNA and histones.

Year of Publication
:
2011
Journal
:
Chemical communications (Cambridge, England)
Volume
:
47
Issue
:
10
Number of Pages
:
2790-2
Date Published
:
2011
ISSN Number
:
1359-7345
URL
:
https://doi.org/10.1039/c0cc05776b
DOI
:
10.1039/c0cc05776b
Short Title
:
Chem Commun (Camb)
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