Dopamine drives binge-like consumption of a palatable food in experimental Parkinsonism.
Author | |
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Abstract | :
Prolonged dopaminergic replacement therapy in PD results in pulsatile dopamine receptors stimulation in both dorsal and ventral striatum causing wearing off, motor fluctuations, and nonmotor side effects such as behavioral addictions. Among impulse control disorders, binge eating can be easily modeled in laboratory animals. |
Year of Publication | :
2019
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Journal | :
Movement disorders : official journal of the Movement Disorder Society
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Volume | :
34
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Issue | :
6
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Number of Pages | :
821-831
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ISSN Number | :
0885-3185
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URL | :
https://doi.org/10.1002/mds.27683
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DOI | :
10.1002/mds.27683
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Short Title | :
Mov Disord
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