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Ofatumumab versus Teriflunomide in Multiple Sclerosis.

Author
Abstract
:

Ofatumumab, a subcutaneous anti-CD20 monoclonal antibody, selectively depletes B cells. Teriflunomide, an oral inhibitor of pyrimidine synthesis, reduces T-cell and B-cell activation. The relative effects of these two drugs in patients with multiple sclerosis are not known.

Year of Publication
:
2020
Journal
:
The New England journal of medicine
Volume
:
383
Issue
:
6
Number of Pages
:
546-557
Date Published
:
2020
ISSN Number
:
0028-4793
URL
:
https://www.nejm.org/doi/10.1056/NEJMoa1917246?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
DOI
:
10.1056/NEJMoa1917246
Short Title
:
N Engl J Med
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