RNA-Seq reveals inflammatory mechanisms of Xiao-Ban-Xia-Tang decoction to ameliorate cisplatin-induced emesis in a rat pica model.
| Author | |
|---|---|
| Abstract | :
Xiao-Ban-Xia-Tang decoction (XBXT), an antiemetic formula in traditional Chinese medicine, has been proved to be a potential treatment for chemotherapy-induced nausea and vomiting (CINV), but the underlying mechanisms are not adequately understood. This study aimed to investigate changes in the ileum transcriptome after cisplatin and XBXT treatment and to reveal whether the antiemetic mechanisms of XBXT are related to its anti-inflammatory effect. |
| Year of Publication | :
2020
|
| Journal | :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|
| Volume | :
131
|
| Number of Pages | :
110699
|
| ISSN Number | :
0753-3322
|
| URL | :
https://linkinghub.elsevier.com/retrieve/pii/S0753-3322(20)30892-1
|
| DOI | :
10.1016/j.biopha.2020.110699
|
| Short Title | :
Biomed Pharmacother
|
| Download citation |