Intramuscular AZD7442 (Tixagevimab-Cilgavimab) for Prevention of Covid-19.
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Abstract | :
The monoclonal-antibody combination AZD7442 is composed of tixagevimab and cilgavimab, two neutralizing antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that have an extended half-life and have been shown to have prophylactic and therapeutic effects in animal models. Pharmacokinetic data in humans indicate that AZD7442 has an extended half-life of approximately 90 days. |
Year of Publication | :
2022
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Journal | :
The New England journal of medicine
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Volume | :
386
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Issue | :
23
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Number of Pages | :
2188-2200
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Date Published | :
2022
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ISSN Number | :
0028-4793
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URL | :
https://www.nejm.org/doi/10.1056/NEJMoa2116620?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
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DOI | :
10.1056/NEJMoa2116620
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Short Title | :
N Engl J Med
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