Comment on "Differential rescue of light- and food-entrainable circadian rhythms".
| Author | |
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| Abstract | :
Fuller et al. (Reports, 23 May 2008, p. 1074) reported that the dorsomedial hypothalamus contains a Bmal1-based oscillator that can drive food-entrained circadian rhythms. We report that mice bearing a null mutation of Bmal1 exhibit normal food-anticipatory circadian rhythms. Lack of food anticipation in Bmal1-/- mice reported by Fuller et al. may reflect morbidity due to weight loss, thus raising questions about their conclusions. |
| Year of Publication | :
2008
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| Journal | :
Science (New York, N.Y.)
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| Volume | :
322
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| Issue | :
5902
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| Number of Pages | :
675; author reply 675
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| Date Published | :
2008
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| ISSN Number | :
0036-8075
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| URL | :
https:///www.science.org/doi/10.1126/science.1161387?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
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| DOI | :
10.1126/science.1161387
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| Short Title | :
Science
|
| Download citation |